The videos were themed around: program presentation and pain management, hygiene, oral and tube feeding, exercise and mobility, pressure injury prevention, dressing care, spirituality, and grief. The videos were validated by 6 expert judges and twelve patient caregivers. The main difference between the videos produced was their basis in health literacy and digital health literacy as a way to enable caregiver empowerment. The study contributes to society by facilitating caregivers’ adaptation to the demands of palliative care, reducing insecurities and promoting a more humanized environment for the patient and their family, and strengthening the field of digital health literacy.